Institute for Bioprocessing and Analytical
Measurement Techniques, Heilbad Heiligenstadt, Germany (Co-ordinator, Partner
1)
Dr. Klaus Liefeith, Head of the Department of Biomaterials
klaus.liefeith@iba-heiligenstadt.de
iba is a non-profit research institute supported by the Thuringia Ministry of Science,
Research and Art. The institute is organised in three closely linked departments
Biomaterials, Bioprocess Technology and Analytical Measurement Technology. About 50
scientists, first of all engineers, chemists, physicists and biologists, pay particular
attention to applied research and industrial development. The research carried
out at the iba is concentrated in the areas of biomedicine, biotechnology, and the environment
dealing with aspects lie somewhere between basic research and individual market-oriented
research projects. To maintain a high level of knowledge and know-how strategic research
projects are focused first of all to special problems regarding the interface situation
between biomaterials and biosystems.
Special Activities of the Department of Biomaterials:
For a better understanding of the behaviour of materials in biological surroundings, it
is important to learn more about the interaction of biological systems on material
surfaces. That's why the fundamental objective of the research of the department of
biomaterials are the analysis of interaction phenomena in the contact area between
surfaces of artificial and/or natural biomaterials and the adjacent biological environment
(biomolecules, microorganisms, cells) to improve the biofunctionality and the
biocompatibility of biomaterials. In this context one of the main functions of the
specialised department is to study correlations between biocompatibility and measurable
material characteristics, making possible predictions about the behaviour of the materials
within a biosystem.
Contact: http://www.iba-heiligenstadt.de/
Laboratory for Medical Device Evaluation,
Bilthoven, The Netherlands (Partner 2)
Dr. Yvette van Erp
yvette.van.erp@bioScan.nl
BioScan BV is a test- and research laboratory, specialized in biological
safety testing and performance testing. Since 1998 we work in close
cooperation with Factory BV, a full Contract Research Organization offering
clinical trial services for medical devices. These combined services support
our challenge to guide medical device companies over the most efficient track
to registration and market introduction of their medical devices.
Medical device companies will profit from our:
broad experience in medical device evaluation
knowledge of most recent developments in the regulatory and
standardization field word wide
high level of professionalism that is realized by a network of experts
BioScan offers:
Guidance in the selection of appropriate testing programs
Standard biocompatibility tests in vitro and in vivo according to ISO
10993
In vivo functionality studies
Organization and monitoring of clinical studies according to GCP, EN 540
and/or ISO 14155
Implementation and consultancy for quality systems
Histopathological evaluation
Microbiological evaluations
Sterility tests
Sterilization facilities
Research and development under ISO 9001 and/or GLP
Our customers can rely on our accurate, competent and client oriented
services since we operate in compliance with GLP, GCP and ISO 9001.
Contact: http://www.bioscan.nl/
Martin-Luther-University Halle-Wittenberg, Halle, Germany (Partner 3)
Dr. Ulrich Rothe
PD Dr. Rothe is head of the working group 'model membranes', which is associated to the
Institute of Physiological Chemistry of the MLU. The group is working with archaebacterial
lipids, which are amphiphilic compounds with two charge centers separated by a
double-chain C 40 phythanyl spacer. One of his main interests is the development of
methods for lipid coupling onto solid surfaces of plastics and other materials coming in
direct tissue contact in order to make these biomaterials more biocompatible and to avoid
severe side effects and immunological reactions. The incorporation of biological active
molecules (peptides, antibodies, enzymes, glycolipids) into these bioactive lipid-coatings
is one of the most promising research concepts.
Contact: http://www.medizin.uni-halle.de/ipc/
Developers of
Products for Medical Applications, Enschede, The
Netherlands (Partner 4)
Ir. Theo Klijn, Managing Director
th.klijn@humeca.nl
The Humeca consulting group was founded in 1981 and specialized itself in
the fields of materials- (e.g. polymer-) and medical engineering.
Within these fields Humeca offers:
- feasibility studies - development and improvement of products and
processes - research and trouble-shooting - development, production and supply
of medical products
Contact: th.klijn@humeca.nl
www.humeca.nl
The Foundation for Scientific and Industrial Research at the Norwegian
Institute of Technology, Trondheim, Norway (Partner 5)
Dr. Ruth Schmid, Senior Research Scientist, Head of the Group of Polymer
Chemistry, Department of Chemical Engineering
Ruth.B.Schmid@sintef.no
The SINTEF Group performs contract research and development for industry and the public
sector in the fields of technology transfer, natural and social sciences. With approx.
1.800 employees and an annual turnover of NOK 1.5 billion, SINTEF is one of Europe's
largest independent research organisations. Contracts from the public and private sectors
provide 92% of the operating revenue. The Department of Polymer Chemistry is part of the
research institute SINTEF Applied Chemistry, which has approx. 180 employees and a
turnover of NOK 160 mill, and is organised in 10 departments, covering a wide range of
chemical disciplines.
Contact: http://www.sintef.no/
Dipartimento di Informatica Sistemistica e Telematica Universitΰ di Genova,
Genova, Italy (Partner 6)
Prof. Carmelina Ruggiero
carmelina.ruggiero@unige.it
The Bioengineering and Medical Informatics Laboratory is associated to the Department
of Informatics, Systems and Telematics of the University of Genova and has been active for
many years in several bioengineering fields, such as: medical and biological informatics;
molecular and cellular engineering, determination of protein structures and biomedical
modelling. The group is mainly interested in theoretical modelling of interaction forces
respectively energies between several molecules and molecules and different solids by
computer modelling. Recently published results concerning protein adsorption and cell
adhesion should be transferred to microbial adhesion processes. The laboratory has already
participated in some projects funded by the EU.
Contact: http://www.medinfo.dist.unige.it/
